Descubren en Israel nuevos remedios contra el Parkinson

Israel-El-descubrimiento-de-nuevos-farmacos-para-la-enfermedad-de-Parkinson-ilusiona-la-promesa-de-impedir-la-progresion-de-la-enfermedad- Vis a Vis
Israel-El-descubrimiento-de-nuevos-farmacos-para-la-enfermedad-de-Parkinson-ilusiona-la-promesa-de-impedir-la-progresion-de-la-enfermedad- Vis a Vis

El descubrimiento de nuevos fármacos para la enfermedad de Parkinson ilusiona la promesa de impedir la progresión de la enfermedad.

Investigadores de Israel han descubierto que las proteínas llamadas BMP5 / 7 son nuevas terapias potenciales (y prometedoras) para combatir la enfermedad de Parkinson. Se piensa que podrían cambiar la trayectoria del trastorno. Estos hallazgos se publicaron recientemente en la prestigiosa revista de neurología clínica Brain.

La enfermedad de Parkinson afecta a más de 10 millones de personas en todo el mundo. Se caracteriza por la degeneración progresiva de las células cerebrales secretoras de dopamina que provoca graves alteraciones del movimiento.

Hoy en día, se cree que la proteína alfa-sinucleína, que está presente en todos los cerebros humanos, juega un papel central en el desarrollo de la enfermedad de Parkinson al plegarse mal y formar grumos tóxicos en las células cerebrales secretoras de dopamina de los individuos afectados.

Actualmente, todas las terapias utilizadas para la enfermedad de Parkinson mejoran los síntomas.

Sin embargo, su eficacia es inaceptablemente baja en las etapas avanzadas de la enfermedad y lamentablemente, no detienen ni ralentizan la progresión de la enfermedad.

El Dr. Claude Brodski, MD y su equipo descubrieron que en las células cerebrales productoras de dopamina de pacientes con enfermedad de Parkinson, la señalización de BMP5 / 7 se redujo significativamente.

Leer más: Investigadores israelíes descubren un medicamento “natural” para tratar la osteoporosis.

Es un cambio que posiblemente podría contribuir al desarrollo de la enfermedad. Para estudiar esta posibilidad, los científicos diseñaron genéticamente cerebros de ratones para reducir la señalización de BMP5 / 7 en las células cerebrales productoras de dopamina.

Confirmando su sospecha, la reducción de la señalización de BMP5 / 7 de hecho conduce a una acumulación de grupos tóxicos de alfa-sinucleína y pérdida de células cerebrales productoras de dopamina.

Luego, los investigadores plantearon la hipótesis de que si la falta de señalización de BMP5 / 7 provoca la pérdida de células cerebrales productoras de dopamina, la administración de BMP5 / 7 podría proteger estas células en un modelo de enfermedad de Parkinson.

“De hecho, descubrimos que el tratamiento con BMP5 / 7 puede, en un modelo de ratón con enfermedad de Parkinson, prevenir de manera eficiente la acumulación de alfa-sinucleína, la pérdida de células cerebrales productoras de dopamina y las alteraciones del movimiento asociadas.

Estos hallazgos son muy interesantes, ya que sugieren que BMP5 / 7 podría ralentizar o detener la progresión de la enfermedad de Parkinson.

Actualmente, estamos centrando todos nuestros esfuerzos en acercar nuestro descubrimiento a la aplicación clínica ”, dice el Dr. Brodski.

El Dr. Galit Mazooz Perlmuter, dijo: “existe una gran necesidad insatisfecha de nuevas terapias para tratar la enfermedad de Parkinson. Especialmente en las etapas avanzadas de la enfermedad. Los hallazgos del Dr. Brodski, aunque en las primeras etapas, ofrecen un objetivo farmacológico para la enfermedad que abordará el mecanismo de esta condición devastadora. Ahora estamos buscando un socio industrial para un mayor desarrollo de esta invención pendiente de patente”.

Latam Israel


  1. Hey! I just wanted to ask if you ever have any problems with hackers?
    My last blog (wordpress) was hacked and I ended up losing several weeks of hard work due to no data backup.
    Do you have any methods to stop hackers? asmr 0mniartist

  2. Its like you learn my thoughts! You seem to understand so much approximately this, such as you wrote the e-book in it or something.
    I believe that you could do with a few percent to force the message home a bit, however instead of that, that is excellent blog.

    An excellent read. I will definitely be back. asmr 0mniartist

  3. Excellent post. I was checking constantly this weblog and I’m inspired!
    Extremely useful information specially the remaining phase :
    ) I handle such info a lot. I was seeking this particular info for a very lengthy time.
    Thanks and best of luck. asmr 0mniartist

  4. Greetings! I know this is kinda off topic but I was wondering
    if you knew where I could get a captcha plugin for my comment
    form? I’m using the same blog platform as yours and I’m having difficulty finding one?
    Thanks a lot!

  5. Hi there, this weekend is fastidious in favor of me, as
    this occasion i am reading this enormous informative
    paragraph here at my residence. 0mniartist asmr

  6. Undeniably believe that which you said. Your favorite justification appeared to be on the
    net the simplest thing to be aware of. I say to you, I
    certainly get annoyed while people think about worries that they just do
    not know about. You managed to hit the nail upon the top and defined
    out the whole thing without having side effect , people could take a signal.
    Will probably be back to get more. Thanks

  7. Hurrah! Finally I got a blog from where I know how to genuinely get valuable information concerning my study and knowledge.

  8. Please let me know if you’re looking for a writer for your
    blog. You have some really good articles and I think I would be a good asset.

    If you ever want to take some of the load off, I’d absolutely love
    to write some content for your blog in exchange for a link back to mine.
    Please send me an email if interested. Many thanks!

    Look into my webpage scr888 kiss918

  9. I’m not that much of a online reader to be honest but
    your sites really nice, keep it up! I’ll
    go ahead and bookmark your site to come back in the future.
    Many thanks

  10. Hello there! This blog post could not be written much better!
    Going through this article reminds me of my
    previous roommate! He constantly kept talking about this.
    I’ll send this post to him. Pretty sure he will have a very good read.

    I appreciate you for sharing!

    Review my blog post: Download joker123 Apk

  11. Hi I am so delighted I found your weblog, I really found you by error, while
    I was searching on Bing for something else, Anyways I am here now and would just like to say thank you for a marvelous post and a all
    round exciting blog (I also love the theme/design), I don’t have time
    to look over it all at the moment but I have book-marked
    it and also included your RSS feeds, so when I have time
    I will be back to read more, Please do keep up the excellent work.

  12. Hi there, just became alert to your blog through Google, and
    found that it is really informative. I’m going to watch out for
    brussels. I will be grateful if you continue this in future.
    Lots of people will be benefited from your writing. Cheers!

  13. Right here is the right blog for anyone who wishes to find out about this topic.
    You understand a whole lot its almost hard to argue with you (not that I actually will need to…HaHa).

    You definitely put a brand new spin on a topic which has been discussed for a
    long time. Wonderful stuff, just excellent!

  14. Its like you read my mind! You seem to grasp so much about this, like you wrote the book in it or something.

    I think that you simply can do with a few percent to force
    the message home a little bit, but other than that, this is magnificent blog.
    A great read. I will definitely be back.

  15. Ⲩou really make it apρear reallу easy along with your
    presentatіon but I in finding this mattger to Ьe actᥙally something which
    I think I might by no means understand. It sort of feels too
    complex аnd extremely wide foг me. I am taқing a
    looк forward for your subsequent submit, I will try to get thee cling of it!

  16. Thanks for your marvelous posting! I seriously enjoyed reading it, you may be a great author.I will always bookmark your blog and
    will come back later in life. I want to encourage you to continue your great job,
    have a nice evening!

  17. Greеting frkm Los angeles! I’m bored to tears аt work so I dеcided to browse your blog on my iphone during lunch bгeak.
    Ireally like the info you proviⅾe here and can’t waut tto take a ⅼook
    when I get home. I’m amazed at how quck үour blog loaded on my mobile ..
    I’m not evеn ᥙsijng WIFI, just 3G .. Anywаys,
    аmazing blօg!

  18. It’s a pity you don’t have a donate button! I’d without a doubt
    donate to this outstanding blog! I guess for now i’ll settle for book-marking and adding your RSS feed to my Google account.
    I look forward to fresh updates and will talk about this website with
    my Facebook group. Talk soon!

  19. I really like what you guys are usually up too.
    This kind of clever work and reporting! Keep up the fantastic
    works guys I’ve you guys to my blogroll.

  20. If some one wants expert view about blogging and site-building after that i recommend him/her to visit this web site, Keep up the pleasant work.

  21. Aw, this was a very nice post. Taking the time and actual
    effort to create a great article… but what
    can I say… I hesitate a lot and don’t manage to get
    anything done.

  22. I read this piece of writing completely regarding the resemblance of
    hottest and earlier technologies, it’s amazing article.

  23. My spouse and I absolutely love your blog and find
    the majority of your post’s to be just what I’m looking for.
    can you offer guest writers to write content for you personally?
    I wouldn’t mind creating a post or elaborating on some of the subjects you write regarding here.
    Again, awesome site!

  24. scoliosis
    We stumbled over here by a different page and thought
    I may as well check things out. I like what I see so
    now i’m following you. Look forward to looking at your web page again. scoliosis

  25. scoliosis
    Howdy would you mind sharing which blog platform you’re using?
    I’m planning to start my own blog in the near future
    but I’m having a tough time choosing between BlogEngine/Wordpress/B2evolution and Drupal.

    The reason I ask is because your design seems different then most blogs and
    I’m looking for something unique. P.S Sorry for being
    off-topic but I had to ask! scoliosis

  26. scoliosis
    I am really inspired along with your writing skills and also with the format on your
    blog. Is this a paid topic or did you customize it yourself?
    Either way keep up the excellent high quality writing,
    it’s uncommon to look a great blog like this one these days..

  27. I like the valuable information you provide to your articles.
    I will bookmark your weblog and take a look at again right here regularly.
    I’m reasonably certain I’ll be told plenty of new stuff proper right here!
    Best of luck for the following!

  28. Hi there I am so happy I found your blog page, I really
    found you by mistake, while I was browsing on Yahoo for something else,
    Nonetheless I am here now and would just like to say thank you for
    a marvelous post and a all round enjoyable blog (I also love
    the theme/design), I don’t have time to go through it all at
    the moment but I have bookmarked it and also added
    in your RSS feeds, so when I have time I will be back to read more, Please do keep up the superb b.

  29. Hello just wanted to give you a quick heads up and let you know a few of the pictures aren’t loading correctly.
    I’m not sure why but I think its a linking issue. I’ve tried
    it in two different internet browsers and both show the same results.

  30. This is really interesting, You are an excessively skilled blogger.
    I’ve joined your feed and look ahead to in quest of more of your
    wonderful post. Additionally, I have shared your web site in my social networks


Please enter your comment!
Please enter your name here