Investigadores de Israel han desarrollado un nuevo método para el análisis de sangre. Es más rápido y económico que cualquiera existente para el estudio de la composición química de las muestras de sangre.
Aseguran que puede acelerar el diagnóstico temprano de enfermedades.
La primera aplicación que se probará será la detección temprana de varios tumores cancerosos con base en análisis de sangre.
La tecnología innovadora, que se publicó en Nature Communications, fue desarrollada por el profesor Tomer Shlomi y los estudiantes de doctorado Shoval Lagziel y Boris Sarvin.
Leer más: La ciencia israelí busca suprimir el tratamiento de diálisis
Se basa en una combinación única de espectrometría de masas y métodos computacionales desarrollados por el grupo de investigación.
Análisis de sangre 98% mas rápidos y baratos.
Un espectrómetro de masas es un dispositivo común utilizado para determinar las concentraciones de moléculas en muestras biológicas.
Las pruebas con este dispositivo generalmente requieren un proceso preliminar llamado cromatografía. Eso implica la separación de los materiales en la muestra de acuerdo con las propiedades químicas.
La cromatografía, que aumenta la sensibilidad de la medición espectrométrica, lleva mucho tiempo y, por lo tanto, hace que el proceso sea costoso.
Una muestra generalmente cuesta cientos de dólares.
Como resultado, es deseable encontrar una manera de saltear el paso cromatográfico sin comprometer la sensibilidad del análisis.
Es decir, mantener la capacidad de identificar muchas moléculas y cuantificar sus concentraciones.
En el estudio actual, el grupo de investigación del profesor Shlomi presenta un método que omite el paso de la cromatografía. Pero permite utilizar directamente la espectrometría de masas sin afectar significativamente la calidad del análisis.
La prueba se completa en solo 30 segundos, lo que acorta el proceso en aproximadamente un 98% y reduce su costo en una tasa similar.
Según el profesor Shlomi, la novedad radica en el uso de un método computacional desarrollado por el grupo de investigación.
Emplean un método que identifica configuraciones de trabajo óptimas en el espectrómetro de masas, lo que permite un análisis de alta sensibilidad para tipos específicos de muestras biológicas.
El análisis computacional también corrige la información bruta medida y cuantifica con precisión las concentraciones de miles de moléculas en muestras de sangre.
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