Un estudio israelí reveló que personas trasplantadas no desarrollaron anticuerpos pese a haber sido vacunadas

Personas trasplantadas no desarrollaron anticuerpos pese a la vacuna
Personas trasplantadas no desarrollaron anticuerpos pese a la vacuna

Un estudio israelí reveló que personas trasplantadas no desarrollaron anticuerpos pese a haber recibido la vacuna.

La inmunidad contra el COVID-19 de las llamadas personas de riesgo desvela a las autoridades sanitarias de todo el mundo. Es que los mayores de 60 años, junto con quienes padecen enfermedades preexistentes, y entre ellos aquellos que fueron sometidos en el pasado a un trasplante de órgano figuran entre los prioritarios a la hora de recibir una vacuna para prevenir el coronavirus.

En este contexto, recientes investigaciones realizadas en los hospitales israelíes Beilinson y Sheba de Tel Hashomer detectaron que se registró una disminución en la cantidad de anticuerpos contra el coronavirus en las personas que atravesaron en el pasado trasplantes, pese a haber recibido las dosis de las vacunas.

Es así que el 82% entre quienes recibieron un trasplante de pulmones no desarrolló anticuerpos en la cantidad suficiente, incluso tras haber recibido el esquema completo de vacunación.

Ruthi Rajmimov, directora del Servicio de Trasplante de Riñón del Beilinson, habló con los medios israelíes. Dijo que se realizó un estudio con alrededor de 300 receptores de trasplantes. «Se encontró que alrededor del 75% de ellos no desarrollaron anticuerpos en respuesta a la vacuna”, aseguró.

“Los receptores de los trasplantes pensaron que estaban vacunados después de recibir las dosis de la vacuna, y de hecho salieron del aislamiento y ahora estamos viendo una ola de morbilidad severa e incluso mortalidad entre los receptores de trasplantes de riñón”, indicó.

Los investigadores descubrieron así que los receptores de trasplantes de órganos pueden seguir teniendo un alto riesgo de contraer COVID-19. Esto es incluso después de estar completamente vacunados contra el nuevo coronavirus.

Uno de los estudios israelíes analizaron las respuestas humorales de 139 receptores de trasplante de riñón. Todos estos después de recibir ambas inyecciones de la vacuna Pfizer-BioNTech. Compararon sus resultados con un grupo de control de 25 participantes sanos informó Infobae.

Uno de los estudios israelíes analizaron las respuestas humorales de 139 receptores de trasplante de riñón después de recibir ambas inyecciones de la vacuna Pfizer-BioNTech (Reuters)Uno de los estudios israelíes analizaron las respuestas humorales de 139 receptores de trasplante de riñón después de recibir ambas inyecciones de la vacuna Pfizer-BioNTech (Reuters)

Todos los participantes del grupo de control mostraron una respuesta de anticuerpos positiva a la proteína de pico. Sólo 51 de los 136 (37,5%) receptores de trasplantes de órganos tuvieron serología positiva.

En general, los niveles medios de anticuerpos “fueron significativamente más bajos” en comparación con los participantes de control, dijeron los investigadores. Los receptores de trasplantes que de hecho mostraron una serología positiva eran típicamente más jóvenes que los que no lo tenían.

Además, el periodo de tiempo más largo entre el trasplante y la vacunación se asoció significativamente con una respuesta serológica positiva a las vacunas de ARNm.

“Los factores de predicción más importantes de la imposibilidad de generar una respuesta humoral en nuestra cohorte de receptores de trasplante de riñón fueron la edad avanzada. También la necesidad de corticosteroides en dosis altas durante el último año (previo a la vacunación). A su vez, el mantenimiento con tres medicamentos inmunosupresores y un régimen que incluye Micofenolato de mofetilo MMF”. Eso escribieron los autores del estudio, según publicó The Jerusalem Post, explicaron cuáles 

Profunda tristeza por el fallecimiento de Mario Jaraz Z’L

Los investigadores agregaron que se sabe que el MMF tiene un “efecto supresor sobre el sistema inmunológico. Esto incluye la inhibición de la producción de anticuerpos». Señalaron que “cuanto mayor es el grado de inmunosupresión, es menos probable que el paciente responda a la inmunización”.

De los 139 participantes del estudio, sólo dos desarrollaron infecciones graves por COVID-19 después de una vacunación completa. Uno requirió hospitalización severa 12 semanas después de ser vacunado. El otro murió nueve semanas después de recibir la segunda dosis de la vacuna Pfizer.

Los receptores de trasplantes que mostraron una serología positiva eran típicamente más jóvenes que los que no lo tenían (Efe)

Los receptores de trasplantes que mostraron una serología positiva eran típicamente más jóvenes que los que no lo tenían (Efe)
El Gran Rabino Davidovich viajó a Mar del Plata para otorgar un guet

Las tasas de respuesta reducidas a las vacunas entre los receptores de trasplantes se documentaron bien. Esto fue a través de estudios publicados anteriormente que cubren otras vacunas comunes. Como las que protegen contra la hepatitis B, la gripe o las antineumocócicas.

Si bien el estudio confirma hallazgos anteriores, los investigadores señalan que es necesario realizar más investigaciones para determinar si los pacientes con estos niveles serológicos bajos tienen un mayor riesgo de contraer coronavirus y cuál sería la gravedad de la enfermedad si es así, considerando que no ha habido un “umbral de anticuerpos protectores” bien establecido.

Los investigadores recomiendan que los receptores de trasplantes de órganos reciban asesoramiento sobre su propia inmunización personal. También que adopten un “enfoque individual” del asunto. Esto es además de seguir practicando el distanciamiento social y otras medidas para protegerse contra las infecciones por COVID-19.

La razón por la que los receptores de trasplantes están incluidos entre los pacientes de riesgo es que los tratamientos que reciben para que su cuerpo no rechace el órgano trasplantado, deterioran la capacidad del sistema inmunológico para desarrollar los anticuerpos en respuesta a la vacuna. Aún se desconoce la cantidad de anticuerpos desarrollados por los pacientes sometidos a quimioterapia.

 

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  103. มีกลุ่มนักเดิมพัน: กลุ่มนักเดิมพัน ให้คำปรึกษา แชร์ประสบการณ์

  104. มีสูตรสอนเล่น: สูตรสอนเล่นมากมาย เพิ่มทักษะการเดิมพัน

  105. เล่นได้เงินจริง: เดิมพันแล้วได้เงินจริง ถอนได้ไว

  106. เล่นได้ทุกที่ทุกเวลา: รองรับการเล่นผ่านมือถือ เล่นง่าย สะดวก ทุกที่ทุกเวลา

  107. เล่นได้อย่างมีรางวัล: เล่นเกมเดิมพัน ลุ้นรับรางวัลมากมาย

  108. Ufabet เว็บพนันออนไลน์ที่บริการดีเยี่ยม: ทีมงานมืออาชีพ คอยให้บริการตลอด 24 ชั่วโมง ตอบคำถาม แก้ไขปัญหา รวดเร็ว ทันใจ

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  110. อัตราต่อรองดีที่สุด: อัตราต่อรองดีที่สุด ให้ราคาสูง

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  112. มีสูตรสอนเล่น: สูตรสอนเล่นมากมาย เพิ่มทักษะการเดิมพัน

  113. Ufabet เว็บพนันออนไลน์ที่บริการดีเยี่ยม: ทีมงานมืออาชีพ คอยให้บริการตลอด 24 ชั่วโมง ตอบคำถาม แก้ไขปัญหา รวดเร็ว ทันใจ

  114. ติดตามทุกแมตช์: ดูบาสสด ติดตามทุกแมตช์ บาสเก็ตบอลทุกลีก ทุกรายการ ครบจบในที่เดียว

  115. เล่นได้เงินจริง: เดิมพันแล้วได้เงินจริง ถอนได้ไว

  116. เล่นได้อย่างมั่นใจ: เว็บไซต์มาตรฐาน ปลอดภัย มั่นใจได้

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  118. ความปลอดภัย: ดูบาสสด ระบบความปลอดภัยสูง ปกป้องข้อมูลส่วนตัว มั่นใจได้ทุกการใช้งาน

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  128. บริษัทของเรามีแพ็กเกจทำเว็บไซต์ที่ครอบคลุมทุกความต้องการ ไม่ว่า…ธุรกิจของคุณจะมีขนาดเล็กหรือใหญ่ เราพร้อมให้คำแนะนำฟรี

  129. สำหรับแฟนบอลที่ชื่นชอบการเดิมพัน คุณสามารถ ดูบอลสด ไปพร้อมกับการวิเคราะห์แนวโน้มของเกม

  130. ประโยชน์และข้อดีในการเล่นเกมสล็อตกับเว็บ สล็อต pg ทดลองเล่นฟรี ของเรา

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